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Phenytoin-associated thrombocytopenia in a toddler
F K Alehan1, E C Russell, J M Pellock
1Division of Child Neurology, Medical College of Virginia of Virginia Commonwealth University, Richmond 23298-0211, USA.
Journal of Child Neurology
|March 12, 1999
Abstract:
Hematologic side effects are rare side effects of treatment with phenytoin. We report a 2-year-old girl who developed reversible thrombocytopenia following treatment with phenytoin. Thrombocytopenia as a side effect of phenytoin treatment has usually been reported in adults and generally occurs 2 to 4 weeks after initiation of therapy. In our case, the thrombocytopenia developed on the 11th day of therapy and resolved 5 days after discontinuation of the phenytoin.