Related Experiment Videos
RNA splicing: more clues from spinal muscular atrophy
1Department of Genetics Center for Human Genetics Program in Cell Biology Case Western Reserve University University Hospitals of Cleveland Cleveland Ohio 44106-4955 USA. gxm26@po.cwru.edu
Current Biology : CB
|March 13, 1999
Abstract:
Spinal muscular atrophy is caused by mutations in the SMN1 gene, the product of which is part of a multi-component complex involved in the assembly of small nuclear ribonucleoproteins. A recent study indicates that SMN may also play a role in pre-mRNA splicing.