[Osteopoikilosos (author's transl)]

In Rumania, 26 cases of osteopoikilosis (20 males, 6 females) have been discovered. Five of these cases were familial (hereditary). Only 1 patient also had disseminated lenticular dermatofibrosis. All of the cases were discovered accidentally. All of the cases exibited the classic form of osteopoikilosis with stippling. Evaluation of the cases showed that various osteopoikilosis could be found in the same family and that probably the appearance of the condensation zones was related to the type of stress to which the bones are subjected (particularly pressure). Many cases show a tendency toward calcification in other tissues and not just in the bones (costal cartilage, periosteal reactions, lungs). In one case, a biopsy was made and a swelling of the trabeculae of the bone as well as cartilagenous proliferation was established.