Oligofructose stimulates calcium absorption in adolescents

Area of Science:

• Nutrition Science
• Human Physiology
• Dietary Fiber Research

Background:

• Nondigestible oligosaccharides, like oligofructose, are known to stimulate calcium absorption in rats.
• Previous studies indicated that this effect extends to human subjects, suggesting potential benefits for bone health.

Purpose of the Study:

• To determine if a daily intake of 15 grams of oligofructose stimulates calcium absorption in adolescent males.
• To investigate the impact of oligofructose supplementation on mineral bioavailability in a key developmental stage.

Main Methods:

• A randomized, double-blind, crossover study involving 12 healthy male adolescents (aged 14-16).
• Participants consumed 15 g of oligofructose or sucrose (control) daily for 9 days, with a 19-day washout period.
• Calcium absorption was measured using the 44Ca and 48Ca isotope tracer method on day 8 of each treatment period.

Main Results:

• Consumption of 15 g of oligofructose per day led to a significant increase in true fractional calcium absorption.
• The mean difference in calcium absorption was 10.8% (±5.6%, P < 0.05, one-sided) compared to the control (sucrose).

Conclusions:

• Daily intake of 15 grams of oligofructose effectively stimulates fractional calcium absorption in male adolescents.
• Oligofructose may be a beneficial dietary component for improving calcium bioavailability and supporting bone health during adolescence.