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Published on: April 9, 2015
[Phage types of typhoid cultures of the Orel region in 1964-1973]
Abstract:
A total of 810 cultures of the causative agents of typhoid fever were isolated at the territory of the Orel region in 1964-1973 in 655 foci; the phage type was established in 63.5% of the cases, 30.2% of the cultures could not be typed by the available phages, and the rest were polylysable or devoid of Vi-antigen (W-form). A total of 16 phage types were revealed; among them there prevailed phage types A (18%), E (15.1%), F1 (7.3%), and N (5.2%); phage types 28, 46, and 40 were less frequent; phage types C1, T and D6 were revealed in individual cases only. There occurred no significant changes in the phage pattern for the observation period.
Insights
Typhoid fever (Salmonella Typhi) strains in Orel region showed stable phage types from 1964-1973. Predominant types included A, E, F1, and N, with no significant shifts observed over the decade.
Area of Science:
- Microbiology
- Epidemiology
- Infectious Diseases
Context:
- The Orel region experienced numerous typhoid fever outbreaks between 1964 and 1973.
- Monitoring bacterial pathogens is crucial for public health surveillance.
Purpose:
- To characterize the phage types of Salmonella Typhi isolates from the Orel region.
- To identify prevalent phage types and observe any temporal changes in their distribution.
Summary:
- A total of 810 Salmonella Typhi cultures were analyzed from 655 outbreaks.
- Phage typing was successful for 63.5% of isolates; 30.2% were untypeable.
- Sixteen distinct phage types were identified, with types A, E, F1, and N being the most common.
Impact:
- Establishes a baseline for Salmonella Typhi phage typing in the Orel region.
- Provides insights into the genetic diversity and epidemiological patterns of typhoid fever.
- Informs public health strategies for typhoid fever control and prevention.

