Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Diffuse idiopathic skeletal hyperostosis in the cervical spine.

P R Meyer1

  • 1Department of Orthopaedic Surgery, Northwestern University, Northwestern Memorial Hospital, Chicago, IL 60611, USA.

Clinical Orthopaedics and Related Research
|March 17, 1999
PubMed
Summary

Elderly patients with diffuse idiopathic skeletal hyperostosis-like conditions and neck pain after minor trauma require careful fracture evaluation. Prompt diagnosis and treatment are crucial, as neurological deficits significantly increase mortality risk.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Measurement of internal fixation device support in experimentally produced fractures of the dorsolumbar spine.

Orthopedics·2014
Same author

Differential removal of thymidine nucleotide analogues from blocked DNA chains by human immunodeficiency virus reverse transcriptase in the presence of physiological concentrations of 2'-deoxynucleoside triphosphates.

Antimicrobial agents and chemotherapy·2000
Same author

Emergency, acute, and surgical management of spine trauma.

Archives of physical medicine and rehabilitation·1999
Same author

A mechanism of AZT resistance: an increase in nucleotide-dependent primer unblocking by mutant HIV-1 reverse transcriptase.

Molecular cell·1999
Same author

Management of an unstable lumbar fracture with a laminar split.

Spinal cord·1999
Same author

Unblocking of chain-terminated primer by HIV-1 reverse transcriptase through a nucleotide-dependent mechanism.

Proceedings of the National Academy of Sciences of the United States of America·1998

Area of Science:

  • Orthopedics
  • Neurosurgery
  • Rheumatology

Background:

  • Diffuse idiopathic skeletal hyperostosis (DISH), ankylosing spondylitis, and ossification of the posterior longitudinal ligament share pathological similarities.
  • These conditions can predispose individuals to severe cervical spinal fractures from minor trauma.
  • Fractures may remain undiagnosed until neurological deficits manifest.

Purpose of the Study:

  • To investigate the outcomes of cervical spinal fractures in elderly patients with DISH-like pathologies.
  • To identify risk factors associated with mortality in this patient cohort.

Main Methods:

  • A retrospective study of 29 elderly patients with cervical spinal fractures and DISH-like pathologies.
  • Analysis of treatment approaches (surgical vs. conservative) and neurological status.

Related Experiment Videos

  • Comparison of survival rates based on neurological function and treatment.

    • Main Results:

    • Twenty patients treated surgically had varying neurological outcomes, with three postoperative deaths.
    • Nine patients treated conservatively also showed a range of neurological outcomes.
    • All patients with intact neurological function, regardless of treatment, survived.

    Conclusions:

    • Elderly patients with DISH-like pathology, trivial trauma history, and neck pain warrant thorough fracture examination.
    • Decreased neurological function is a significant predictor of increased mortality in these patients.
    • Early diagnosis and appropriate management are critical for improving outcomes.