Techniques for optimization of pulsatile ventricular assist device support
Related Experiment Video
Updated: Oct 21, 2026

Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
Published on: May 11, 2018
Abstract:
For some time now researchers have argued the efficacy of pulsatile versus nonpulsatile hemodynamic support. Pulsatile systems, while providing a more physiological pumping source, are burdened with a multiparametric output function that can greatly affect the utility of such ventricular assist device (VAD) support. A simplified approach to the optimization of the pulsatile VADs' output function has been developed. This approach yields device outputs of approximately 5.5 L/min at physiologic pressures while demonstrating clinically acceptable blood chemistry. Obtaining this optimal operating point involves the determination of the VAD system output function for a range of fill-enhancing vacuum settings. A quantitative method for evaluating synchronous versus asynchronous pumping modes as related to coronary perfusion is also demonstrated.
More Related Videos
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation (NIPPV)
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...
Heart Failure VI: Adjunct Therapies
Cardiomyopathy V: Interprofessional Care

