On-line cell manipulation for cancer treatment

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Updated: Oct 24, 2026

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics
06:00

Through the Looking Glass: Time-lapse Microscopy and Longitudinal Tracking of Single Cells to Study Anti-cancer Therapeutics

Published on: May 14, 2016

T Tani1, K Numa, H Abe

  • 1First Department of Surgery, Shiga University of Medical Science, Japan.

Artificial Organs
|June 1, 1992
PubMed

We hypothesized that the host immune system is directly stimulated by contact between blood and the materials used in blood purification systems. This concept has never been applied in therapeutic plasmapheresis. Two new materials have been invented since 1983. One of those is lipopolysaccharide (LPS)-immobilized beads, which are chemically bonded bacterial LPS (LPS-B). Another is immobilized pokeweed mitogen (PWM-B). We studied these two materials for their anti-tumor cell activity in vitro and in vivo. Their efficacy on tumor cells was demonstrated to be much stronger than that of lymphocyte activated killer (LAK) cells. Our new concept was proven to be correct.

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