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Linear accelerator radiosurgery for nonacoustic schwannomas.
S R Mabanta1, J M Buatti, W A Friedman
1Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, USA.
Summary
Linear accelerator stereotactic radiosurgery achieved excellent local control for nonacoustic schwannomas. This treatment demonstrated a favorable toxicity profile, supporting its effectiveness in managing these tumors.
Area of Science:
- Neurosurgery
- Radiation Oncology
- Oncology
Background:
- Nonacoustic schwannomas are rare tumors affecting cranial nerves.
- Stereotactic radiosurgery (SRS) offers a non-invasive treatment option.
- Evaluating SRS outcomes for nonacoustic schwannomas is crucial for treatment planning.
Purpose of the Study:
- To analyze the efficacy and safety of linear accelerator stereotactic radiosurgery (LA-SRS) for nonacoustic schwannomas.
- To assess local control rates and toxicity associated with LA-SRS in this patient cohort.
Main Methods:
- Retrospective analysis of 18 patients with nonacoustic schwannomas treated with LA-SRS between 1989 and 1997.
- Tumor locations included jugular foramen, trigeminal, and facial nerves.
- Dose prescription, isocenter planning, and follow-up imaging (MRI) were detailed.
Main Results:
- 100% local control was achieved in all 18 evaluable patients.
- Tumor regression or stable disease was observed in 90% of patients with follow-up MRI.
- Complications were infrequent and manageable, with some patients experiencing improvement in pre-existing deficits.
Conclusions:
- LA-SRS provides excellent preliminary tumor control for nonacoustic schwannomas.
- The treatment exhibits a favorable toxicity profile, supporting its role in managing these tumors.
- LA-SRS is an effective therapeutic option for patients with nonacoustic schwannomas.