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Therapeutic agent for treating dysuria (NC-1800): absolute configuration of the enantiomers
S Yoshida1, M Yamamoto, Y Aoki
1Department of Applied Chemistry, Faculty of Engineering, Saitama University, Japan.
Chirality
|March 18, 1999
Abstract:
The absolute configuration of an enantiomer of the title compound, (+/-)-1. fumaric acid salt, was determined by X-ray crystallographic analysis of (+)-1 [salt of (+)-tartaric acid [(+)-2]]. This salt for X-ray crystallographic analysis was prepared by a simple method. The analysis of (+)-1 [salt of (+)-2] showed that this enantiomer has the 5-S and 1-R absolute configuration. The final R and Rw values were 0.0614 and 0.0713, respectively.