Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

1.4K
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
1.4K
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

1.1K
In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
1.1K
Glaucoma: Overview01:25

Glaucoma: Overview

1.5K
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction to: Predictability of success and open conjunctival revision rates in the subsequent eye after XEN45 Gel Stent implantation according to lens status.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2022
Same author

Predictability of success and open conjunctival revision rates in the subsequent eye after XEN45 Gel Stent implantation according to lens status.

Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie·2022
Same author

Impact of failed ab-interno trabeculectomy (trabectome) on subsequent XEN45 gel stent implantation in pseudophakic eyes.

International ophthalmology·2021
Same author

[Dependency of intraocular pressure on body posture in glaucoma patients : New approaches to pathogenesis and treatment].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2020
Same author

[Glaucoma and nanophthalmos].

Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·2018
Same author

Bruch's membrane opening-based optical coherence tomography of the optic nerve head: a useful diagnostic tool to detect glaucoma in macrodiscs.

Eye (London, England)·2018
Same journal

Metastasis of Nasopharyngeal Squamous Cell Carcinoma to the Angle.

Ophthalmology·2026
Same journal

Endocrine Mucin-Producing Sweat Gland Carcinoma of Eyelid.

Ophthalmology·2026
Same journal

Multimodal Imaging of Optic Nerve Invasion in Unilateral Retinoblastoma.

Ophthalmology·2026
Same journal

Avacincaptad Pegol Slows Progressive Ellipsoid Zone Degradation/Loss in Eyes With Geographic Atrophy.

Ophthalmology·2026
Same journal

Access to Intravitreal Anti-VEGF Drugs in Persons with Medicare Advantage Compared with Medicare Fee-For-Service.

Ophthalmology·2026
Same journal

Re: Dones et al.: Emergency department use of ocular point-of-care ultrasound and its utility in diagnosis at a tertiary academic medical center (Ophthalmology. 2026;133:720-727).

Ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Mar 1, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

2.0K

Microendoscopic trabecular surgery in glaucoma management.

P C Jacobi1, T S Dietlein, G K Krieglstein

  • 1Department of Ophthalmology, University Eye Hospital Cologne, Germany.

Ophthalmology
|March 18, 1999
PubMed
Summary
This summary is machine-generated.

Microendoscopic trabecular surgery safely and effectively manages advanced open-angle glaucoma with corneal opacification. This technique provides clear visualization for procedures like goniocurettage, reducing intraocular pressure and medication needs.

More Related Videos

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.7K

Related Experiment Videos

Last Updated: Mar 1, 2026

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents
10:10

Full-Circle Cauterization of Limbal Vascular Plexus for Surgically Induced Glaucoma in Rodents

Published on: February 15, 2022

2.0K
Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

12.7K
Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation
08:30

Glaucoma-inducing Procedure in an In Vivo Rat Model and Whole-mount Retina Preparation

Published on: March 12, 2016

13.7K

Area of Science:

  • Ophthalmology
  • Surgical Innovation

Background:

  • Advanced chronic open-angle glaucoma often presents challenges in surgical visualization due to corneal opacification.
  • Traditional surgical methods may be limited when direct visualization of the anterior segment is obscured.

Purpose of the Study:

  • To assess the safety and efficacy of microendoscope-controlled trabecular surgery for open-angle glaucoma with corneal opacification.
  • To evaluate the utility of microendoscopy in overcoming visualization barriers in glaucoma surgery.

Main Methods:

  • A comparative interventional case series involving 15 patients with medically uncontrolled open-angle glaucoma and corneal opacification.
  • Trabecular surgery was performed using microendoscopic control, with 7 eyes undergoing photoablative laser goniopuncture and 8 undergoing goniocurettage.
  • Intraocular pressure (IOP) and medication use were measured pre- and post-surgery; complications were analyzed.

Main Results:

  • The ophthalmic microendoscope enabled successful visualization and control of trabecular surgery in all cases.
  • Mean IOP decreased significantly from 34.5 mmHg pre-surgery to 18.5 mmHg at 21 months post-surgery.
  • Average medication use reduced from 2.3 to 1.0, with no significant difference in outcomes between laser and goniocurettage groups. No severe complications were reported.

Conclusions:

  • Microendoscopy provides safe and effective illumination and visualization for anterior chamber angle surgery.
  • This technique facilitates trabecular surgeries like goniocurettage and laser goniopuncture even with corneal opacification.
  • Microendoscopic trabecular surgery offers a potential alternative surgical treatment for select open-angle glaucoma patients.