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Varicella zoster virus ocular disease
1Francis I. Proctor Foundation, Department of Ophthalmology, University of California, San Francisco 94143, USA.
International Ophthalmology Clinics
|March 19, 1999
Summary
Varicella-zoster virus (VZV) causes a widening range of diseases, including inflammatory conditions that may not show typical rash. New antivirals and vaccines offer improved VZV management.
Area of Science:
- Virology
- Infectious Diseases
- Immunology
Background:
- Varicella-zoster virus (VZV) is a common human herpesvirus.
- VZV is primarily known for causing chickenpox and shingles.
- The full spectrum of VZV-associated diseases is still being elucidated.
Purpose of the Study:
- To review the evolving understanding of VZV-related diseases.
- To highlight atypical and emerging VZV manifestations.
- To discuss advancements in VZV diagnosis, treatment, and prevention.
Main Methods:
- Literature review of recent studies on VZV.
- Analysis of diagnostic criteria for VZV infections.
- Evaluation of current and future therapeutic strategies for VZV.
Main Results:
- VZV is implicated in an increasing number of inflammatory conditions.
- Some VZV-related conditions present without the characteristic herpetic rash ('sine herpete').
- Diagnostic capabilities for VZV are improving.
Conclusions:
- The spectrum of VZV diseases is broader than previously recognized.
- Early and accurate diagnosis is crucial for managing VZV complications.
- Antiviral therapies and vaccines are vital for controlling VZV and its sequelae.