Jove
Visualize
Contact Us

Related Experiment Videos

Bladder histological changes associated with chronic indwelling urinary catheter.

K M Delnay1, W H Stonehill, H Goldman

  • 1Department of Urology, University of Tennessee and Veterans Affairs Medical Center, Memphis, USA.

The Journal of Urology
|March 19, 1999
PubMed
Summary

Chronic urinary catheter use in spinal cord injury patients can lead to premalignant bladder changes. Surveillance is crucial due to the significant occurrence of these histological abnormalities and associated malignancies.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Unstimulated inflammatory activity is associated with treatment response to cognitive-behavioral therapy for urologic chronic pelvic pain.

Frontiers in pain research (Lausanne, Switzerland)·2025
Same author

Complications of Synthetic Midurethral Slings: Is There a Relevant Discrepancy Between Observational Data and Clinical Trials?

European urology focus·2023
Same author

Current and future international patterns of care of neurogenic bladder after spinal cord injury.

World journal of urology·2018
Same author

Pre-eclampsia and acute pulmonary embolism-the importance of making a differential diagnosis: a case report.

Journal of anesthesia·2017
Same author

Are we shortchanging frail older people when it comes to the pharmacological treatment of urgency urinary incontinence?

International journal of clinical practice·2014
Same author

Urinary incontinence in women: non-pharmacologic approaches and newer pharmacotherapies.

Minerva medica·2014
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Urology
  • Pathology
  • Spinal Cord Injury Research

Background:

  • Chronic urinary catheterization is common in spinal cord injury patients.
  • Catheter use is associated with bladder inflammation and tissue response.
  • Histological changes in the bladder due to chronic catheterization require elucidation.

Purpose of the Study:

  • To determine the incidence of nonmalignant histological changes in bladder biopsies.
  • To evaluate bladder tissue response in patients with chronic indwelling urinary catheters.
  • To assess the spectrum of pathological conditions associated with long-term catheter use.

Main Methods:

  • Bladder biopsies were performed on 208 spinal cord injured patients over 7 years.
  • Patients had chronic indwelling catheters for neurogenic voiding dysfunction.

Related Experiment Videos

  • Biopsies from multiple bladder sites were analyzed by a pathologist.

    • Main Results:

    • 17 patients had bladder malignancy (squamous cell carcinoma, transitional cell carcinoma, adenocarcinoma).
    • Nonmalignant changes, including premalignant lesions like squamous metaplasia and cystitis glandularis, occurred in 23% of patients.
    • Predominantly inflammatory and squamous pathological conditions were identified.

    Conclusions:

    • This study represents a large evaluation of bladder biopsies in chronic catheter users with spinal cord injury.
    • A range of inflammatory and proliferative changes, including premalignant and malignant conditions, were observed.
    • Ongoing surveillance for mucosal changes is essential in this patient population.