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Related Experiment Videos

Risperidone-induced rabbit syndrome: an unusual movement disorder caused by an atypical antipsychotic.

T Levin1, U Heresco-Levy

  • 1Eitanim Mental Health Center, Tzfon Yehuda, Israel. levint@netvision.net.il

European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology
|March 19, 1999
PubMed
Summary

Rabbit syndrome, a rare neuroleptic side effect, involves rhythmic mouth movements. This case report details risperidone, an atypical antipsychotic, inducing this syndrome for the first time.

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Area of Science:

  • Neuroscience
  • Pharmacology
  • Movement Disorders

Background:

  • Rabbit syndrome is a rare extra-pyramidal side effect linked to chronic neuroleptic use.
  • It is characterized by rapid, fine, rhythmic vertical mouth movements resembling a rabbit's chewing.
  • The condition typically responds well to anticholinergic medications.

Observation:

  • This report presents the first documented case of risperidone, an atypical antipsychotic, inducing Rabbit syndrome.
  • The patient exhibited characteristic oral movements consistent with the syndrome.

Findings:

  • Risperidone, an atypical antipsychotic, can precipitate Rabbit syndrome.
  • This finding challenges previous assumptions about the specific neuroleptic classes associated with the syndrome.

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Implications:

  • The case broadens the understanding of neuroleptic-induced movement disorders.
  • It suggests a need to consider atypical antipsychotics in the differential diagnosis of Rabbit syndrome.
  • Further research is warranted to explore the neurobiological mechanisms underlying this association.