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Related Experiment Videos

Body mass index in glaucoma.

P Gasser1, D Stümpfig, A Schötzau

  • 1University Eye Clinic Basel, Medical Outpatient Department, University Clinic, University Basel, Switzerland.

Journal of Glaucoma
|March 20, 1999
PubMed
Summary
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Obesity does not appear to be a risk factor for open-angle glaucoma or normal-tension glaucoma. Body mass index (BMI) in glaucoma patients showed no statistical difference compared to control subjects.

Area of Science:

  • Ophthalmology
  • Glaucoma Research
  • Metabolic Health

Background:

  • Glaucoma is a leading cause of irreversible blindness worldwide.
  • The role of metabolic factors, such as obesity, in glaucoma pathogenesis is not fully understood.
  • Previous studies have yielded conflicting results regarding the association between body mass index (BMI) and glaucoma.

Purpose of the Study:

  • To investigate the relationship between body mass index (BMI) and glaucoma.
  • Specifically, to compare BMI in patients with open-angle glaucoma (OAG) and normal-tension glaucoma (NTG) with that of control subjects.

Main Methods:

  • A comparative study involving 288 control subjects.
  • BMI was assessed in 42 OAG patients with intraocular pressure (IOP) > 21 mmHg.

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  • BMI was also assessed in 87 OAG patients with IOP ≤ 21 mmHg and progressive damage, and 57 NTG patients.

    • Main Results:

    • No statistically significant difference in BMI was observed between glaucoma patients and control subjects.
    • A trend towards lower BMI was noted in patients with glaucoma compared to controls.
    • This suggests obesity is unlikely to be a contributing factor.

    Conclusions:

    • Obesity does not appear to be a significant risk factor for the development of open-angle glaucoma or normal-tension glaucoma.
    • Further research may explore other metabolic or systemic factors in glaucoma etiology.