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Updated: Aug 19, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Basilar impression complicating osteogenesis imperfecta type IV: the clinical and neuroradiological findings in four
Objectives:
To describe the clinical and neuroradiological features of basilar impression in patients with osteogenesis imperfecta type IV.
Methods:
Four patients with basilar impression were ascertained in a population study of osteogenesis imperfecta. All four had detailed clinical and neuroradiological examination with both CT and MRI of the craniocervical junction and posterior fossa structures.
Results:
All four showed significant compression of the posterior fossa structures and surgical decompression was performed with relief of symptoms.
Conclusion:
Symptoms of cough headache and trigeminal neuralgia occurring in patients with osteogenesis imperfecta are indications for detailed clinical and neuroradiological investigation to document basilar impression.
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