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Unexplained decrease in measured oxygen saturation by pulse oximetry following injection of Lymphazurin 1% (isosulfan
R L Coleman1, C W Whitten, J O'Boyle
1Department of Obstetrics and Gynecology, University of Texas, Southwestern Medical Center, Dallas 75235-9032, USA. rcole1@mednet.swmed.edu
Journal of Surgical Oncology
|March 20, 1999
Summary
A rare case of altered pulse oximetry readings occurred during cervical cancer surgery after dye injection. Arterial blood gas tests confirmed the patient was fine, suggesting dye interference with the pulse oximeter.
Area of Science:
- Oncology
- Medical Devices
- Pharmacology
Background:
- Lymphatic mapping is crucial for staging cervical carcinoma.
- Pulse oximetry is a standard monitoring tool during surgical procedures.
Observation:
- A significant decrease in measured pulse oximetry saturation was noted post-injection of Lymphazurin 1% dye.
- This desaturation effect lasted for approximately 5 minutes.
Findings:
- Arterial blood gas analysis confirmed adequate oxygenation, ruling out actual hypoxemia.
- The observed pulse oximetry alteration is suspected to be due to the dye's spectroscopic properties interfering with the device's wavelengths.
Implications:
- Clinicians should be aware of potential pulse oximetry interference from Lymphazurin dye during lymphatic mapping.
- Further investigation into the interaction between dyes and pulse oximetry technology is warranted for accurate patient monitoring.