Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Leg ulcers: a common problem with sometimes uncommon etiologies.

P H Bowman1, D J Hogan

  • 1University of California, San Francisco, USA.

Geriatrics
|March 23, 1999
PubMed
Summary

Squamous cell carcinoma (SCC) is an uncommon cause of leg ulcers, affecting 600,000 Americans annually. Clinicians should consider SCC in non-healing or atypical leg ulcers, especially in Black populations on lower extremities.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protein kinase D distribution in normal human epidermis, basal cell carcinoma and psoriasis.

The British journal of dermatology·2006
Same author

Evolution of IESs and scrambling in the actin I gene in hypotrichous ciliates.

Proceedings of the National Academy of Sciences of the United States of America·2001
Same author

Mycosis fungoides bullosa: report of a case and review of the literature.

Journal of the American Academy of Dermatology·2001
Same author

Primary multiple miliary osteoma cutis and exogenous ochronosis.

Cutis·2001
Same author

Clearance can be a realistic expectation of psoriasis treatment.

Journal of the American Academy of Dermatology·2001
Same author

Extrafacial granuloma faciale: report of a case and response to treatment.

Cutis·2001

Area of Science:

  • Dermatology
  • Oncology
  • Vascular Medicine

Background:

  • Leg ulcers are a significant health issue in the U.S., with 600,000 new cases yearly.
  • Most leg ulcers stem from venous or arterial conditions.
  • Squamous cell carcinoma (SCC) is a less common but critical cause of leg ulceration.

Observation:

  • SCC incidence is higher in White populations.
  • Black individuals with SCC often present with lesions on non-sun-exposed skin, particularly the lower extremities.
  • Predisposing factors for SCC include burn scars, chronic infections, chronic ulceration, and discoid lupus erythematosus.

Findings:

  • Atypical leg ulcers or those resistant to healing warrant investigation for uncommon causes like SCC.
  • SCC can manifest as a leg ulcer, especially in specific demographic groups and under certain predisposing conditions.

Implications:

  • Early consideration of SCC in non-healing leg ulcers can lead to timely diagnosis and treatment.
  • Recognizing atypical presentations of SCC on the lower extremities is crucial for effective patient management.
  • Understanding risk factors associated with SCC leg ulcers aids in clinical suspicion and diagnostic workup.

Related Experiment Videos