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Updated: Aug 2, 2026

Quantitative Polymerase Chain Reaction (qPCR)-Based Rapid Diagnosis of Helicobacter pylori Infection and Antibiotic Resistance
Published on: July 28, 2023
Scope and consequences of peptic ulcer disease. How important is asymptomatic Helicobacter pylori infection?
D Y Graham1, R E Rakel, A M Fendrick
1Department of Medicine, Baylor College of Medicine, Houston, TX, USA. dygraham@bcm.tmc.com
Abstract:
H pylori infection is so common as to seem ubiquitous in many areas of the world. Transmission is believed to be primarily person to person. The pathogen invariably damages the gastric mucosa, resulting in both structural and functional abnormalities. It causes histologic gastritis and is critical in the pathogenesis of the gastritis-associated diseases, namely, gastric ulcer, duodenal ulcer, gastric adenocarcinoma, and primary gastric lymphoma. Elimination of the infection results in healing of gastritis and cure of peptic ulcer disease.
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