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Fibrogenesis in peritoneal endometriosis. A semi-quantitative analysis of type-I collagen
S Matsuzaki1, M Canis, C Darcha
1Department of Gynecology, Polyclinique de l'Hôtel-Dieu, Clermont-Ferrand, France.
Gynecologic and Obstetric Investigation
|March 24, 1999
Abstract
Objective:
To evaluate the degree of fibrosis in the stroma of peritoneal endometriosis, according to the macroscopic appearance.
Methods:
Red and black lesions of peritoneal endometriosis were collected and type-I collagen was immunohistochemically identified. The percentage of the stained area in the stroma was measured using a computerized image analysis system.
Results:
There was a significant difference in the mean percentage of the total stained area between red and black lesions.
Conclusion:
The amount of type-I collagen is significantly higher in the stroma of black peritoneal lesions than in red peritoneal lesions.