Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Trophic Levels01:35

Trophic Levels

37.7K
All organisms in an ecosystem occupy a trophic level in the food chain. The lowest level consists of primary producers, which synthesize their food from either solar or chemical energy. Each subsequent level obtains energy from the levels below. Detritivores can occupy any of the levels above primary producers.
37.7K
Trophic Efficiency00:46

Trophic Efficiency

25.2K
Trophic level transfer efficiency (TLTE) is a measure of the total energy transfer from one trophic level to the next. Due to extensive energy loss as metabolic heat, an average of only 10% of the original energy obtained is passed on to the next level. This pattern of energy loss severely limits the possible number of trophic levels in a food chain.
25.2K
What is a Sensory System?01:31

What is a Sensory System?

101.2K
Sensory systems detect stimuli—such as light and sound waves—and transduce them into neural signals that can be interpreted by the nervous system. In addition to external stimuli detected by the senses, some sensory systems detect internal stimuli—such as the proprioceptors in muscles and tendons that send feedback about limb position.
101.2K
Sensory Modalities01:15

Sensory Modalities

3.9K
Sensation typically is the process by which the sensory receptors and sense organs detect stimuli from the internal and external environment and transmit this information to the central nervous system for processing.
General senses refer to the broad category of sensory information detected by receptors in the body and can be further grouped into somatic and visceral senses. Somatic sensations include touch, pressure, temperature, and pain and are essential for navigating our environment and...
3.9K
Sensory Memory01:14

Sensory Memory

706
Sensory memory captures information from the environment in its original form for a very brief duration, just long enough to be exposed to visual, auditory, and other senses. This type of memory is detailed and rich but quickly lost unless certain strategies are employed to transfer it into short-term or long-term memory. Sensory information is continuously bombarding the human brain, yet only a small fraction is absorbed, as most of it does not significantly impact daily life. For instance,...
706
Introduction to Sensory Receptors01:31

Introduction to Sensory Receptors

8.1K
Sensory receptors are vital in our ability to perceive and interpret the world. Sensory receptors are specialized cells in the peripheral nervous system that respond to various stimuli and enable one to experience different sensations. Based on specific criteria, sensory receptors are classified into distinct types.
The first classification criterion is based on cell type, position, and function. Some receptor cells are neurons with free nerve endings, where their dendrites are embedded in the...
8.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rapid quasi-periodic oscillations in the relativistic jet of BL Lacertae.

Nature·2022
Same author

An Introduction to an Evolutionary Tail: EvoDevo, Structure, and Function of Post-Anal Appendages.

Integrative and comparative biology·2021
Same author

Future Tail Tales: A Forward-Looking, Integrative Perspective on Tail Research.

Integrative and comparative biology·2021
Same author

Fiber inline Mach-Zehnder interferometer based on femtosecond laser inscribed waveguides.

Optics letters·2017
Same author

Multimode fiber tip Fabry-Perot cavity for highly sensitive pressure measurement.

Scientific reports·2017
Same author

Crescent shaped Fabry-Perot fiber cavity for ultra-sensitive strain measurement.

Scientific reports·2016

Related Experiment Video

Updated: Feb 9, 2026

Purification of Fibroblasts and Schwann Cells from Sensory and Motor Nerves in Vitro
08:16

Purification of Fibroblasts and Schwann Cells from Sensory and Motor Nerves in Vitro

Published on: May 20, 2020

7.9K

Trophic interactions between sensory nerves and their targets.

W P Chen1, Y C Chang, S T Hsieh

  • 1Department of Anatomy, National Taiwan University College of Medicine, Taipei, Taiwan.

Journal of Biomedical Science
|March 24, 1999
PubMed
Summary

Neurotrophins like nerve growth factor (NGF) and neurotrophin-3 (NT-3) are vital for sensory neuron survival and function. Their therapeutic potential for nerve disorders is being explored.

More Related Videos

A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice
07:08

A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice

Published on: April 19, 2016

13.9K
Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones
10:25

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones

Published on: January 26, 2012

23.8K

Related Experiment Videos

Last Updated: Feb 9, 2026

Purification of Fibroblasts and Schwann Cells from Sensory and Motor Nerves in Vitro
08:16

Purification of Fibroblasts and Schwann Cells from Sensory and Motor Nerves in Vitro

Published on: May 20, 2020

7.9K
A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice
07:08

A Method to Target and Isolate Airway-innervating Sensory Neurons in Mice

Published on: April 19, 2016

13.9K
Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones
10:25

Tissue Preparation and Immunostaining of Mouse Sensory Nerve Fibers Innervating Skin and Limb Bones

Published on: January 26, 2012

23.8K

Area of Science:

  • Neuroscience
  • Cell Biology
  • Developmental Biology

Background:

  • Neurotrophins are critical for neuronal survival and maintenance.
  • Nerve growth factor (NGF) and neurotrophin-3 (NT-3) are key for sensory neurons.
  • Neurotrophins signal via p75 and trk receptors (trk A for NGF, trk C for NT-3).

Purpose of the Study:

  • To elucidate the roles of NGF and NT-3 in sensory neuron development and function.
  • To investigate the interaction between nociceptive nerves and skin.
  • To explore the therapeutic potential of neurotrophic factors for peripheral nerve disorders.

Main Methods:

  • Classification of dorsal root ganglion sensory neurons (large and small).
  • Analysis of receptor expression (trk A, trk C) and neurotrophin dependence.
  • Observation of epidermal changes in denervated skin and effects of neurotrophic factor administration in animal models.

Main Results:

  • Large sensory neurons (trk C+) depend on NT-3 for development and position sensation.
  • Small sensory neurons (trk A+) depend on NGF for nociception (pain and thermal stimuli).
  • Denervation leads to epidermal thinning; neurotrophic factors improve nerve disorder outcomes in animals.

Conclusions:

  • NGF and NT-3 play distinct, crucial roles in sensory neuron subtypes.
  • Bidirectional communication between nociceptive nerves and skin influences skin integrity.
  • Neurotrophic factors show promise for treating human peripheral nerve disorders.