[Serological and clinical aspects of mass transfusion]

Massive transfusion of cold blood causes hemodinamic disturbances because of its acidity, surplus of potassium and defiency of calcium. Negative influence also results from stronger viscosity of blood, from the change of the active substances of blood coagulation, change of the patient's coagulation system responding to the transfused blood, subclinical troubles in this system according to the degree of the shock, reduced ability of oxygen transport caused by viscous blood, poor microcirculation etcr. Arrythmia, bradycardia, fibrilation of heart ventricles, may occur. Vasoconstrictions, microembolism and other incidents may appear. The quality of preserved blood changes during the conservation is changed, potassium and ATP are the indicators for its quality. At massive transfusions blood has to be warmed, filtered through special filters, to the patient has to be given just the quality of blood he needs etcr. The transfusiologist can help the therapist with useful advices and informations for the patient's sake.