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Expanded polytetrafluoroethylene threads for lip augmentation induce foreign body granulomatous reaction
M G Hubmer1, C Hoffmann, H Popper
1Department of Plastic Surgery, Institute of Pathology, University Hospital Graz, Austria.
Plastic and Reconstructive Surgery
|March 24, 1999
Summary
Facial augmentation with expanded polytetrafluoroethylene (e-PTFE) threads, despite being bioinert, can lead to foreign body granulomas. Surgeons must inform patients about this risk of granulomatous reaction.
Area of Science:
- Plastic Surgery
- Biomaterials Science
Background:
- Patient demands for facial aesthetic surgery are high, necessitating effective augmentation materials.
- Alloplastic materials for facial and lip augmentation carry risks including migration, allergic reactions, and foreign body granuloma formation.
Observation:
- Expanded polytetrafluoroethylene (e-PTFE) is considered a highly bioinert alloplastic material.
- Despite its bioinert nature, e-PTFE has been observed to induce foreign body granuloma formation.
Findings:
- The study demonstrates that e-PTFE threads, used for facial augmentation, can elicit a foreign body granulomatous reaction.
- This reaction can manifest as visible and painful nodules, causing patient discomfort and dissatisfaction.
Implications:
- Surgeons utilizing e-PTFE threads for facial augmentation must be aware of the potential for inducing foreign body granulomatous reactions.
- Informed consent is crucial, requiring surgeons to educate patients about the risks associated with e-PTFE threads, including granuloma formation.

