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A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

A new scoring system for the detailed description of the distribution and thrombotic burden in deep leg vein

O Björgell1, P E Nilsson, P J Svensson

  • 1Department of Diagnostic Radiology, University Hospital in Malmö, Sweden.

Angiology
|March 24, 1999
PubMed

Insights

A new scoring system for deep vein thrombosis (DVT) accurately captures thrombotic burden by including all major leg and pelvic veins, unlike the Marder system which often underestimates DVT severity.

Area of Science:

  • Vascular Medicine
  • Radiology
  • Medical Imaging

Background:

  • The Marder system, commonly used for deep vein thrombosis (DVT) research, has limitations.
  • It excludes key deep vein segments, leading to underestimation of thrombotic burden and potential false-negative results.

Purpose of the Study:

  • To develop and validate a novel scoring and distribution system for DVT.
  • This new system aims to encompass all major deep veins in the leg and pelvis for comprehensive research applications.

Main Methods:

  • A prospective, comparative study involving 247 patients.
  • 105 patients with positive phlebography were analyzed using the new system and compared to the Marder system.

Main Results:

  • The Marder system significantly underestimated DVT distribution and thrombotic burden in 72% of patients.
  • 12% of DVT cases were missed entirely by the Marder system, classified as false-negative.
  • The new system successfully scored all DVTs and relevant vein segments, providing a complete assessment.

Conclusions:

  • The developed scoring system offers a more comprehensive and accurate method for assessing DVT.
  • It addresses the limitations of previous systems by including all critical deep vein segments.
  • This enhanced system is crucial for accurate DVT research and understanding deep vein insufficiency progression.

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