A complex translocation involving chromosomes 2, 9 and 22 in a patient with chronic myeloid leukemia

A patient with a high leukocyte count, diagnosed with chronic myeloid leukemia was referred for cytogenetic study. Peripheral blood and bone marrow cells were cultured without mitogenic stimulation. All karyotypes represented rare, varient Philadelphia chromosome with-three way translocation, i.e. t (2; 9; 22) (p13; q34; q11).