Related Experiment Videos
A man with a swollen leg and abnormal globulins
D T Parnassa1, G Matfin, H M Adelman
1Department of Medicine, University of South Florida College of Medicine, Tampa, USA.
Hospital Practice (1995)
|March 25, 1999
Summary
A 72-year-old man experienced leg swelling and shortness of breath after taking NSAIDs. These symptoms persisted despite discontinuing the medication, suggesting a potential link to underlying cardiovascular issues.
Area of Science:
- Cardiology
- Pharmacology
Background:
- Exertional dyspnea and leg swelling are common cardiovascular symptoms.
- Nonsteroidal anti-inflammatory drugs (NSAIDs) can have cardiovascular side effects.
Observation:
- A 72-year-old male presented with a two-week history of exertional dyspnea and right lower leg pain and swelling.
- Symptoms persisted despite NSAID cessation.
- Patient reported a history of two-pillow orthopnea.
Findings:
- The patient's symptoms suggest a possible link between NSAID use and fluid retention or worsening cardiac function.
- The persistence of symptoms after NSAID withdrawal warrants further investigation into underlying conditions.
Implications:
- This case highlights the importance of considering NSAID-induced fluid retention in patients with cardiovascular risk factors.
- Further investigation is crucial to differentiate between NSAID side effects and progression of underlying heart disease.