Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Calcium signalling in glial cells.

J W Deitmer1, A J Verkhratsky, C Lohr

  • 1Abteilung für Allgemeine Zoologie, Universität Kaiserslautern, Kaiserslautern, Germany.

Cell Calcium
|March 26, 1999
PubMed
Summary

Glial cells use calcium signals for communication, forming waves that spread between cells. These signals integrate neuronal and glial activity, impacting brain information processing.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of selection on immune regulatory elements and MHC gene diversity in Holstein cattle.

Journal of dairy science·2026
Same author

Corrigendum to "Completing a worldwide picture: Preliminary evidence of lead exposure in a scavenging bird from mainland Australia" [Sci. Total Environ. 715 (2020) 135913].

The Science of the total environment·2020
Same author

Diagnostic accuracy, validity, and reliability of Tensiomyography to assess muscle function and exercise-induced fatigue in healthy participants. A systematic review with meta-analysis.

Journal of electromyography and kinesiology : official journal of the International Society of Electrophysiological Kinesiology·2019
Same author

Carbonic anhydrases and their functional differences in human and mouse sperm physiology.

Biochemical and biophysical research communications·2015
Same author

Purkinje cell loss and motor coordination defects in profilin1 mutant mice.

Neuroscience·2012
Same author

Primary synovial osteochondromatosis of the stifle in an English Mastiff.

Veterinary and comparative orthopaedics and traumatology : V.C.O.T·2012

Area of Science:

  • Neuroscience
  • Cell Biology
  • Biochemistry

Background:

  • Glial cells respond to stimuli via calcium signals.
  • Glial cells possess receptors and ion channels for calcium signaling.
  • Calcium signals propagate within glial cells and between them, forming intercellular waves.

Purpose of the Study:

  • To investigate the role of glial calcium signals in intercellular communication.
  • To understand how glial calcium waves mediate information exchange in glial networks.
  • To explore the integration of glial and neuronal activity through calcium signaling.

Main Methods:

  • Analysis of glial cell responses to various stimuli.
  • Investigation of receptor and ion channel involvement in calcium signaling.
  • Study of intracellular calcium storage organelles mediating wave propagation.
  • Examination of the interplay between neuronal activity and glial calcium signals.

Main Results:

  • Glial calcium signals are universal responses to stimulation.
  • Intercellular calcium waves facilitate information exchange within glial networks.
  • Propagating calcium waves are mediated by intracellular calcium storage.
  • Glial calcium signals influence neuronal activity and vice versa.

Conclusions:

  • Glial calcium signaling is a fundamental mechanism for intercellular communication.
  • Spreading calcium waves in glia are crucial for information processing in neural networks.
  • Glial calcium signals integrate neuronal and glial compartments, playing a key role in brain function.

Related Experiment Videos