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Osteopenia in female beta-thalassemic patients
C Pafumi1, L Roccasalva, G Pernicone
1Department of Microbiological and Gynecological Science, University of Catania, Italy.
Journal of Pediatric Endocrinology & Metabolism : JPEM
|March 26, 1999
Abstract:
Sixty-four women with thalassemia major aged 13-28 years were studied. 49 patients had primary amenorrhea and 15 had secondary amenorrhea. Bone density of the spine was performed using lunar DPX. The Z score was used to evaluate the degree of osteopenia. In 82% of the patients a Z score less than -2 was found. BMD correlated negatively with the duration of amenorrhea and age of thalassemic patients.