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[Herbal remedies and nephrotoxicity]
J Nortier1, M Depierreux, J L Vanherweghem
1Service de Néphrologie, Hôpital Erasme, U.L.B.
Revue Medicale De Bruxelles
|March 26, 1999
Summary
Many herbal remedies derived from plants can harm the kidneys, leading to acute or chronic renal failure. This review details toxic agents in herbal medicine, focusing on Chinese herbs nephropathy and its complications.
Area of Science:
- Nephrology
- Toxicology
- Herbal Medicine
Context:
- Herbal remedies are widely used globally.
- Plant-derived substances can possess inherent toxicity.
- Renal impairment is a potential adverse effect of certain botanicals.
Purpose:
- To review documented cases of herbal medicine-induced nephrotoxicity.
- To identify specific nephrotoxic agents from vegetal sources.
- To elucidate the clinical spectrum of herbal nephropathy.
Summary:
- Numerous plant-derived substances used in herbal remedies can cause kidney damage.
- This review covers instances of acute or chronic renal failure linked to specific toxic agents identified through toxicologic studies.
- Chinese herbs nephropathy is detailed, including epidemiology, histology, and associated extrarenal and neoplastic complications.
Impact:
- Highlights the potential renal risks associated with herbal medicine consumption.
- Provides critical information for clinicians diagnosing and managing nephrotoxicity.
- Emphasizes the need for rigorous toxicologic evaluation of herbal products.