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Periodinates: a new class of protein tyrosine phosphatase inhibitors

K W Leung¹, B I Posner, G Just

¹Department of Chemistry, McGill University, Montreal, Canada.

Bioorganic & Medicinal Chemistry Letters

|March 26, 1999

Abstract:

A series of periodinates has been synthesized and tested as protein tyrosine phosphatase substrates. Their potency is comparable to or higher than that of vanadates but much lower than that of peroxovanadates.

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