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Serotonin syndrome in a child after a single dose of fluvoxamine
M Gill1, F LoVecchio, B Selden
1Emergency Medicine Residency Program, Maricopa Medical Center, and Samaritan Regional Poison Center, Phoenix Children's Hospital, Phoenix, AZ, USA.
Annals of Emergency Medicine
|March 27, 1999
Abstract:
Serotonin syndrome, a potentially fatal iatrogenic complication of psychopharmacologic therapy, is most commonly reported with combinations of serotonergic medications. Serotonin syndrome is characterized by alterations in cognition, behavior, autonomic, and central nervous system function as a result of increased postsynaptic serotonin receptor agonism. We present the first reported case of serotonin syndrome after a single dose of fluvoxamine in a pediatric patient after ingestion of a single supratherapeutic dose of fluvoxamine.