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[The role of nitric oxide in normal and pathologic immunologic reactions]
B Zdzisińska1, M Kandefer-Szerszeń
1Zakład Wirusologii i Immunologii Instytutu Mikrobiologii i Biotechnologii Uniwersytetu Marii Curie-Skłodowskiej, Lublinie.
Postepy Higieny I Medycyny Doswiadczalnej
|March 27, 1999
Abstract:
Nitric oxide is intercellular messenger that performs a number of important functions, including neurotransmission, vasodilation, inhibition of platelet aggregation and modulation of leukocyte adhesion. The paper presents a new aspects of NO synthesis regulation by bacterial products and cytokines. Problems concerning the role of NO in antimicrobial/antitumor resistance and pathomechanisms of autoimmune diseases are also discussed.