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Related Experiment Videos

Controlled introduction of selenium into Chlorella cells.

S de Alcantara1, C C Lopes, K Wagener

  • 1Institute of Chemistry, Federal University of Rio de Janeiro, Brazil.

Indian Journal of Experimental Biology
|March 27, 1999
PubMed
Summary

Chlorella efficiently absorbs selenium (Se), an essential antioxidant, into its cells. After 24-48 hours, 40% of the absorbed selenium is organically bound within the algae, making it bioavailable for human health.

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Area of Science:

  • Biochemistry and Nutritional Science
  • Algal Biotechnology
  • Trace Element Metabolism

Background:

  • Selenium (Se) is a crucial element for the human body's antioxidant defense system.
  • Chlorella algae possess known therapeutic properties and are explored as a natural carrier for essential nutrients.
  • Organic selenium is preferred for human absorption and utilization compared to inorganic forms.

Purpose of the Study:

  • To investigate the kinetics of selenium absorption by growing Chlorella algal cells.
  • To determine the distribution and form of selenium within the algal cells.
  • To assess the potential of Chlorella as a source of organic selenium for human consumption.

Main Methods:

  • Utilized radioactive 75Se isotope to trace selenium uptake and distribution in Chlorella.

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  • Monitored selenium absorption rates over time, focusing on initial rapid uptake and long-term fixation.
  • Analyzed the final state of selenium within algal cells after 24-48 hours of exposure.

    • Main Results:

    • Rapid initial absorption of selenium occurred within minutes, with irreversible fixation at the cell surface.
    • This surface-bound selenium is not bioavailable for human absorption.
    • After 24-48 hours, approximately 40% of the total fixed selenium was located inside the cells in the desired organic-bound form.

    Conclusions:

    • Chlorella demonstrates significant capacity for absorbing and organically binding selenium.
    • A substantial portion of selenium is internalized and converted into a bioavailable form within 24-48 hours.
    • Chlorella serves as a promising natural vehicle for delivering organic selenium, enhancing its nutritional value.