Internal bleaching with 10% carbamide peroxide in vitro

This in vitro study assessed the efficacy of 10% carbamide peroxide to internally bleach discolored teeth. Following pulp removal, 38 tooth crowns were stained with erythrocytes and bleached 3 times over 14 days using either 10% carbamide peroxide or 30% H2O2 and sodium perborate. The pulp chambers were subsequently filled, and the tooth crowns stored for 3 months. The shades of the crowns were measured using reflectance spectroscopy prior to and at several time points following bleaching. Using statistical analysis, the authors determined that both materials significantly improved the shade of the crowns, and that 10% carbamide peroxide could be utilized clinically to internally bleach nonvital discolored teeth.