Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Helicobacter pylori screening in a general practice].

M Hollenz1, M Stolte, J Labenz

  • 1Institut für Pathologie, Klinikum Bayreuth.

Deutsche Medizinische Wochenschrift (1946)
|March 27, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Gastro-oesophageal reflux disease-update 2021].

Der Internist·2020
Same author

[EndoStim® treatment-a new minimally invasive technology in antireflux surgery].

Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen·2018
Same author

Acute sedation-associated complications in GI endoscopy (ProSed 2 Study): results from the prospective multicentre electronic registry of sedation-associated complications.

Gut·2018
Same author

[Gastroenterological diseases as triggers of chest pain].

Der Internist·2016
Same author

[Barrett's esophagus].

Der Internist·2016
Same author

[Diagnostic and therapeutic management of helicobacter pylori: a survey among German gastroenterologists in private practice].

Zeitschrift fur Gastroenterologie·2016

Asymptomatic Helicobacter pylori (Hp) infections are common and linked to gastrointestinal abnormalities. A 13C-urea breath test is a suitable noninvasive screening method for public health.

Area of Science:

  • Gastroenterology
  • Infectious Diseases
  • Public Health

Background:

  • The clinical significance of Helicobacter pylori (Hp) infection in asymptomatic individuals remains largely undetermined.
  • Noninvasive screening methods for Hp infection require further evaluation for diagnostic and therapeutic relevance.

Purpose of the Study:

  • To assess the diagnostic and therapeutic relevance of noninvasive Helicobacter pylori screening in asymptomatic individuals.
  • To evaluate the practicality and validity of a whole-blood serological test for Hp detection.

Main Methods:

  • A prospective study included 100 consecutive patients from a general medical practice.
  • Noninvasive diagnostics involved a whole-blood serological test and a 13C-urea breath test.
  • Upper gastrointestinal endoscopy was offered for positive noninvasive test results.

Related Experiment Videos

Main Results:

  • Helicobacter pylori prevalence was 40%, increasing with age.
  • The serological test showed predictive values below 80% when compared to the breath test.
  • Eleven patients (23.4%) had clinically significant abnormalities upon endoscopy, with four confirmed Hp infections.

Conclusions:

  • Asymptomatic individuals with Hp infection often present with clinically abnormal upper gastrointestinal findings.
  • Further large-scale, multi-center studies are needed to analyze the cost-effectiveness of noninvasive Hp screening as a public health measure.
  • The 13C-urea breath test is a suitable candidate for noninvasive Hp screening in asymptomatic populations.