[Use of snake venom proteins in medicine]
Related Experiment Video
Updated: Oct 24, 2026

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production
Published on: October 6, 2023
Abstract:
Snakes feed exclusively on freshly killed prey animals which, following their immobilization, have to be swallowed whole. Venomous snakes effect prey immobilization by injection of their venom. Snake venoms are highly concentrated, complex mixtures of individual proteins which, either as enzymes, enzyme effectors or blocking ligands, acting as single agents or in synergistic conjunction with other venom components, modify vital structures of the prey organism to destroy their biological function. Predominantly neurotoxic venoms paralyze respiratory activity by pre- or postsynaptic blockade of neuromuscular transmission. Predominantly haemocytotoxic snake venoms contain components which interact with proteins of the haemostasis, kallikrein or complement system, causing blood volume loss, hypotension or intravascular coagulation which finally lead to circulatory failure. Several isolated snake venom proteins with a known mode of action have found practical application as pharmaceutical agents, diagnostic reagents or preparative tools in the field of haemostaseology, neurobiology and complement research.
More Related Videos
10:25Extraction of Venom and Venom Gland Microdissections from Spiders for Proteomic and Transcriptomic Analyses
Published on: November 3, 2014
12:16High Throughput Quantitative Expression Screening and Purification Applied to Recombinant Disulfide-rich Venom Proteins Produced in E. coli
Published on: July 30, 2014
Related Concept Videos
Role of Proteins in the Human Body
Proteins and Amino Acids
Skeletal Muscle Relaxants: Therapeutic Uses
Recombinant DNA Technology
Antidotes
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
Signal Sequences and Sorting Receptors