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Related Experiment Videos

Low risk of bacteremia in febrile children with recognizable viral syndromes.

D S Greenes1, M B Harper

  • 1Department of Pediatrics, Harvard Medical School, Children's Hospital, Boston, MA 02115, USA. greenes@a1.tch.harvard.edu

The Pediatric Infectious Disease Journal
|March 27, 1999
PubMed
Summary

Febrile children aged 3 to 36 months with recognizable viral syndromes (RVS) have a very low rate of bacteremia. Blood cultures are not necessary for these children with uncomplicated conditions like croup or bronchiolitis.

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Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Epidemiology

Background:

  • Occult bacteremia studies in children often exclude those with viral illnesses.
  • Limited data exists on bacteremia rates in febrile children presenting with recognizable viral syndromes (RVS).

Purpose of the Study:

  • To determine the incidence of bacteremia in children aged 3 to 36 months who have fever and RVS.

Main Methods:

  • Retrospective analysis of pediatric patients (3-36 months) with fever (≥39°C).
  • Identified RVS cases including croup, varicella, bronchiolitis, or stomatitis without concurrent bacterial infection.
  • Assessed bacteremia rates using blood cultures from RVS patients.

Main Results:

  • Out of 21,216 febrile children, 1347 (6%) had RVS.

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  • Blood cultures were performed on 876 RVS patients (65%).
  • True pathogens were identified in only 2 of 876 (0.2%) RVS patients, with specific rates for bronchiolitis (0.2%), croup (0%), stomatitis (0%), and varicella (1.1%).

    • Conclusions:

    • Febrile children (3-36 months) with uncomplicated RVS (croup, bronchiolitis, varicella, stomatitis) exhibit a very low bacteremia rate.
    • Routine blood cultures may not be indicated for these pediatric patients.