[Healing of skin wounds (electronoptic study)]

Tissue specimens of 46 skin wounds were taken on day 8 after a surgical operation to be given an electronoptic examination. The results were evaluated according to age groups. The best healing was the corium showing a prepondenrance of the epidermis had been regenerated with the corium showing a prepondenrance of the proliferation of fibroblasts most of them oriented across the wound direction. Nevertheless, there was a wrong neocolagen fibre orientation with the corium joined mainly by amorphous intercellular substance, probably non-fibrous soluble collangen. - Older subjects were found to have slowed down exudative and macrophagic reactions which were then seen interfering withe the proliferation of fibroblasts and their proteosynthetic activity. To a certain extent, a similar situation was also observed in children where, too, the precipitate exudative reaction was seen interfering in the fibroproliferative phase.