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Related Experiment Videos

Towards safer drug use in general practice.

I D Steven1, A Malpass, J Moller

  • 1Research and Health Promotion, Royal Australian College of General Practitioners, St Peters, SA.

Journal of Quality in Clinical Practice
|March 30, 1999
PubMed
Summary

Medication problems are common in general practice, with many adverse drug events (ADE) stemming from therapeutic use and contraindications. Computer decision support systems could prevent a third of these patient safety issues.

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Area of Science:

  • General Practice
  • Patient Safety
  • Pharmacovigilance

Background:

  • Incident monitoring in general practice is crucial for identifying patient harm.
  • Medication-related errors represent a significant portion of adverse events.

Purpose of the Study:

  • To identify and characterize events or circumstances that could harm patients in general practice.
  • To quantify medication problems and adverse drug events (ADE) in this setting.

Main Methods:

  • Voluntary, anonymous incident-monitoring study.
  • Involved 673 general practitioners reporting 2582 incidents.
  • Analysis focused on medication problems and identified 1556 ADEs.

Main Results:

  • Half of all reports (1294) involved medication problems.

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  • Problems with therapeutic use (26%) and contraindicated medications (15%) were more common than in hospitals.
  • Specific contraindications included allergies (4%), drug interactions (4%), and pathophysiological factors (4%).

    • Conclusions:

    • Medication errors pose a substantial risk in general practice.
    • Computer-based prescribing with decision support may reduce these problems by at least one-third.
    • Further research is needed to develop and implement preventive strategies for patient safety.