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[Hormonal regulation of the Ca+ transport in blood and vascular cells]
1School of Medicine, Moscow State University, Vorobyevy Gory, Russia.
Abstract:
The main pathways of regulation of cytoplasm Ca2+ level with hormones and growth factors, as well as mechanisms of regulation of G-proteins, phospholipase C, Ca-channels, adenylate cyclase, guanylate cyclase, and protein kinase C, are discussed. Regulation of cytoplasm Ca2+ in vascular and blood cells with inositol phosphates, cAMP and cGMP, is stressed. The review summarises data on membrane receptors, G-proteins, protein kinases and their targets involved in regulation of Ca2+ turnover in platelets, endothelial and smooth muscle cells.
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