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Related Experiment Videos

Solid-state fermentation in rotating drum bioreactors: operating variables affect performance through their effects

D M Stuart1, D A Mitchell, M R Johns

  • 1Centre for Instrumental and Developmental Chemistry, School of Natural Resource Sciences, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001, Australia. d.stuart@qut.edu.au

Biotechnology and Bioengineering
|April 1, 1999
PubMed
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Solid-state fermentation (SSF) bioreactor performance depends on operational variables affecting transport phenomena. Substrate characteristics influence these processes, impacting fungal growth and overall SSF efficiency.

Area of Science:

  • Biotechnology
  • Microbial Engineering
  • Bioprocess Engineering

Background:

  • Solid-state fermentation (SSF) is a key bioprocess utilizing microbial growth on solid substrates.
  • Optimizing SSF bioreactor operation is crucial for efficient industrial applications.
  • Understanding the interplay between operational parameters and substrate properties is essential for process control.

Purpose of the Study:

  • To investigate the impact of bioreactor operational variables on fungal growth during SSF.
  • To elucidate the role of transport phenomena (mixing, shear, heat, and mass transfer) in SSF performance.
  • To determine how substrate characteristics influence the effectiveness of transport processes in SSF.

Main Methods:

  • Cultivation of Aspergillus oryzae ACM 4996 in 18.7 L rotating drum bioreactors.

Related Experiment Videos

  • Comparison of fungal growth on an artificial gel-based substrate versus steamed wheat bran.
  • Evaluation of different operational conditions, including rotational speed and agitation (static vs. agitated).

    • Main Results:

    • On gel substrate, increased rotational speed led to decreased fungal growth, likely due to shear stress.
    • On wheat bran, agitated conditions promoted fungal growth over static conditions, indicating improved heat and mass transfer.
    • Transport phenomena and substrate properties were identified as critical factors influencing SSF performance.

    Conclusions:

    • Bioreactor operational variables significantly impact SSF performance by altering transport phenomena.
    • Substrate characteristics dictate the necessity and rates of transport processes, influencing which phenomena become rate-limiting.
    • This study enhances the understanding of bioreactor operation effects on SSF, paving the way for optimized bioprocesses.