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103Pd loaded cartridge air kerma strength verification
D E Mellenberg1, E C Pennington
1Department of Radiology, University of Iowa, Iowa City, USA.
Summary
A new method using applicator cartridges safely calibrates radioactive seeds for prostate cancer treatment. This technique expedites source assays and reduces radiation exposure for physicists and dosimetrists.
Area of Science:
- Medical Physics
- Radiation Oncology
Background:
- Brachytherapy using Iodine-125 (125I) or Palladium-103 (103Pd) seeds is a common prostate cancer treatment.
- Increased use leads to higher workloads and radiation exposure for physicists and dosimetrists during source strength assays.
Purpose of the Study:
- To develop a safer and more efficient method for calibrating radioactive seeds used in brachytherapy.
- To reduce radiation exposure to healthcare professionals handling these radioactive sources.
Main Methods:
- A novel method utilizing applicator cartridges for source calibration was developed.
- Loaded cartridges (5-15 seeds) are placed in a standard well ionization chamber for readings.
- Ionization readings are converted to air kerma source strengths, incorporating experimentally derived correction factors.
Main Results:
- The new method allows for safe handling and expedited assays of 125I and 103Pd seeds.
- Excellent agreement was found between individual seed air kerma strength and manufacturer specifications.
- The technique validates accurate air kerma source strength determination from seed shipments.
Conclusions:
- The applicator cartridge method provides a valid and reliable approach for radioactive seed calibration.
- This method enhances safety and efficiency in brachytherapy quality assurance for prostate cancer treatment.