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[Pulmonary manifestations associated with malaria].

P Hovette1, P Camara, P R Burgel

  • 1Services médicaux, l'Hôpital Principal de Dakar, Sénégal.

Revue De Pneumologie Clinique
|April 1, 1999
PubMed
Summary

Severe malaria can cause acute respiratory distress, a leading cause of mortality in children. Early recognition and treatment are crucial, as delays can be fatal. Prevention involves fluid and output monitoring.

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Area of Science:

  • Tropical Medicine
  • Pediatrics
  • Pulmonology

Context:

  • Pulmonary manifestations are common in malaria patients, including children, pregnant women, and travelers.
  • The exact pathophysiology of these lung issues is not fully understood.
  • Acute respiratory distress in children is a leading cause of mortality in severe malaria.

Purpose:

  • To elucidate the pathophysiology of pulmonary manifestations in malaria.
  • To highlight the diagnostic challenges and potential fatal outcomes of delayed treatment.
  • To outline preventative and therapeutic strategies for malaria-associated pulmonary complications.

Summary:

  • Pulmonary issues in malaria stem from interactions between parasitized red blood cells and lung endothelium.
  • While bronchitis and pneumonia may not directly worsen outcomes, delayed diagnosis can be fatal.

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  • Acute respiratory distress in children is the primary cause of mortality in severe malaria, preceding neurological complications.

    • Impact:

    • Understanding the pathophysiology can lead to targeted treatments for malaria-induced lung injury.
    • Emphasizing early diagnosis and treatment of respiratory symptoms can reduce malaria-related mortality.
    • Implementing preventative measures like fluid management and monitoring can mitigate pulmonary complications.