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[Injectable progesterone in hormone replacement therapy in menopause]
F Patacchiola1, G Porzio, G Carta
1Dipartimento di Discipline Chirurgiche, Università degli Studi de L'Aquila, Italia.
Purpose:
To evaluate activity and tolerability of intramuscular administration of 17-alpha-hydroxyprogesterone caproate (Lentogest-Amsa) in hormone replacement therapy in menopause.
Patients And Methods:
Intramuscular slow releasing 17-alpha-hydroxyprogesterone caproate was given to 30 postmenopausal women. Patients were divided into two groups according to the number of monthly doses (1 or 2).
Results:
In both groups of patients a regular monthly bleeding was obtained. Echographic assessment did not show abnormal endometrial thickness.
Conclusions:
The results of this study have pointed out the efficacy of intramuscular progesterone-caproate administration with a better compliance in the single dose group.