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Intra-arterial thrombolysis for perioperative stroke after open heart surgery
I L Katzan1, T J Masaryk, A J Furlan
1Cerebrovascular Center, Department of Neurology, Cleveland Clinic Foundation, OH 44195, USA.
Neurology
|April 2, 1999
Summary
Intra-arterial thrombolysis may be safe for acute ischemic stroke patients after major surgery. This treatment can be an option for perioperative cerebral embolism, even with recent open heart surgery.
Area of Science:
- Neurology
- Cardiovascular Surgery
- Interventional Radiology
Background:
- Recent major surgery is a contraindication for thrombolysis in acute ischemic stroke.
- Cerebral embolism is a potential complication following cardiac surgery.
Observation:
- Six patients with acute ischemic stroke underwent intra-arterial thrombolysis post-open heart surgery.
- No significant bleeding complications were observed in most patients.
Findings:
- One patient experienced a small, asymptomatic cerebellar hemorrhage.
- Intra-arterial thrombolysis was successfully performed in this high-risk cohort.
Implications:
- Intra-arterial thrombolysis could be a viable treatment for perioperative cerebral embolism.
- This approach may expand treatment options for stroke patients with recent surgical histories.