A new method for evaluation of karyometrical measurements

From karyometrical measurements performed by us and from investigations of other authors it results that the obtained values of nuclear volumes are smaller than real ones. This is caused by different sectioning planes of measured nuclei. Previously published corrections seem not to reflect the real error as they are based on the analysis of the circle, and not of the sphere. In the presented paper a method is given, which may be applicated to interpretation of the results of morphometrical measurements. The proposed method is based on the well known in statistical analysis 3o rule. The obtained results were applicated to a practical example.