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Updated: Aug 18, 2026

Early Detection of Drug-Induced Renal Hemodynamic Dysfunction Using Sonographic Technology in Rats
Published on: March 11, 2016
High-dose renal pharmacoangiography in the assessment of hypovascular renal neoplasms
Abstract:
From 6% to 25% of primary renal carcinomas are either hypovascular or avascular and are the major source of false negative angiography. High-dose renal pharmacoangiography, a valuable adjunct to conventional angiography, combines a renal vasodilator, acetylcholine, with a high dose of contrast medium. High-dose renal pharmacoangiography improves the diagnosis of hypovascular mass by enhancement of tumor vessels, increase of tumor stain, and better opacification of main and collateral renal veins. During a 4 year period, 20 hypovascular renal neoplasms were studied and successfully diagnosed preoperatively by this method.
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