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Accidental laboratory infection with Treponema pallidum, Nichols strain
Journal of the American Venereal Disease Association
|December 1, 1976
Abstract:
This case report describes a laboratory-acquired infection with Treponema pallidum, Nichols strain. The specific details of the accidental exposure are presented, along with a description of the clinical observations. This infection indicates that the rabbit adapted Nichols strain of T pallidum retains its capability to infect humans. In addition, aerosols of concentrated preparations of these organisms, generated within the laboratory, represent a definite biohazard.
Insights
A laboratory infection with Treponema pallidum, Nichols strain, highlights the infectious potential of this syphilis-causing bacterium. Concentrated preparations pose a significant biohazard risk in laboratory settings.
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Treponema pallidum is the causative agent of syphilis.
- The Nichols strain is a commonly used laboratory strain.
- Laboratory-acquired infections (LAIs) are a concern in microbiology.