Spontaneous alterations in the size of lymph nodes after lymphography

A total of 124 normal nodes in 20 patients with Hodgkin's disease were measured in lymphograms by means of planimetry with point counting. Anteroposterior views were used both in the lymphography (24h) and at subsequent check-up studies. A statistically significant reduction (p is less than 0.05) of 3.5 per cent in the area of the lymph nodes was observed in the period after lymphography (range, 4-189 days; average, 26.8 days) during which no irradiation or chemotherapy had been given. Correction for technical factors and an evaluation of errors of measurement were made.