Related Experiment Video
Updated: Aug 3, 2026

12:08
Improving IV Insulin Administration in a Community Hospital
Published on: June 11, 2012
How a CQI program improved aminoglycoside use in a community hospital
1College of Pharmacy, University of Geogia, Athens.
Summary
This study evaluated amikacin sulfate use at a regional medical center. Appropriate prescribing of aminoglycosides can lead to significant cost savings.
Area of Science:
- Pharmacology
- Clinical Pharmacy
- Health Economics
Background:
- The P & T Committee of a 285-bed, non-tertiary care regional medical center initiated a study.
- Evaluation of aminoglycoside use is crucial for optimizing patient care and resource allocation.
Purpose of the Study:
- To assess the utilization patterns of amikacin sulfate (Amikin).
- To determine the impact of an educational intervention on aminoglycoside prescribing.
- To estimate potential annual cost savings through appropriate aminoglycoside use.
Main Methods:
- A Drug Utilization Evaluation (DUE) was conducted.
- An educational initiative was implemented.
- Cost analysis was performed based on prescribing data.
Main Results:
- Results from an initial DUE are presented.
- Outcomes following the educational effort are detailed.
- Estimated annual cost savings associated with appropriate aminoglycoside prescribing are reported.
Conclusions:
- Appropriate prescribing of aminoglycosides, including amikacin sulfate, can lead to substantial cost savings.
- Educational interventions can positively influence drug utilization patterns.
- Ongoing monitoring by P & T Committees is vital for cost-effective medication management.
More Related Videos
Related Concept Videos
Antibiotic Selection
Overview
Healthcare Associated Infections II: Preventive Measures
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Nursing Clinical Information System
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
Gentamicin, an aminoglycoside antibiotic, is commonly administered via intermittent intravenous infusion to treat severe infections. An intermittent one-hour infusion of gentamicin, administered at eight-hour intervals, allows for precise control of plasma drug concentrations, minimizing toxicity while ensuring therapeutic efficacy. Pharmacokinetic principles govern the dynamics of plasma concentrations and can be mathematically described using specific equations.The plasma drug concentration...
Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Gene Regulation in Microbial Communities: Quorum Sensing
Quorum sensing is a mechanism of bacterial communication that enables coordinated gene expression in response to changes in population density. This facilitates collective behaviors that enhance survival, resource acquisition, and ecological adaptation. This process relies on small signaling molecules called autoinducers that accumulate as bacterial populations grow. When a critical threshold concentration of autoinducers is reached, bacterial cells collectively modify gene expression,...

